Retina International's Scientific Newsletter

	Retina International's Scientific Newsletter
	Protein Pages Proteins of Unknown Function Underlying Retinal Disorders

Recent update: 14.08.2002

When the first mutations in proteins causing retinal disorders where discovered, their function and properties where mostly known and could be correlated with functions in the retinal biochemistry. Currently, positional cloning and the growing information content of Genebank have provided a tool to discover genes of unknown function causing retinal disorders. They are usually characterised only by functional domains or homologous sequences common to proteins of known function. Among these genes are:

	Bestrophin		EGF-containing fibrillin-like extracellular matrix protein 1 (EFEMP1)
	RP1-Gene		RP2-Gene
	Aryl Hydrocarbon Receptor-interacting Protein-like 1		Multidrug Resistance-associated Protein 6 (ABCC6/MPR6)
	Tubby-like Protein 1 (TULP1)		Nyctalopin (NYX)

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Contact the editor	This site is maintained and edited by Dr. rer. medic. Markus Preising, Dipl.Biol. Molecular Genetics Laboratory Department of Paediatric Ophthalmology, Strabismology and Ophthalmogenetics University of Regensburg Head: Prof. Dr. med. Birgit Lorenz